Our organization is testing the effects of infusing donor dendritic cells into a patient one week before performing a living-donor liver transplant.
Dendritic cells can control the response of other immune system cells, so dendritic cells from the liver donor can control the recipient’s immune response to the transplanted organ.
We expect that the donor’s immune system cells will teach the recipient’s immune system to accept the new organ and reduce the need for long-term immunosuppression.
Initiated by the UPMC Immune Transplant and Therapy Center.