• Newsroom
  • Contact Us
UPMC | Immune Transplant and Therapy Center
  • About Us
  • Aging
  • Cancer
  • Chronic Diseases
    • Autoimmunity
    • Chronic Anemias
  • Transplant
  • Clinical Trials
  • Newsroom
  • Contact Us

UPMC Transplant Services The Aging Institute UPMC Hillman Cancer Center

DCreg in Living Donor Liver Transplantation (NCT03164265)

Our organization is testing the effects of infusing donor dendritic cells into a patient one week before performing a living-donor liver transplant.

Dendritic cells can control the response of other immune system cells, so dendritic cells from the liver donor can control the recipient’s immune response to the transplanted organ.

We expect that the donor’s immune system cells will teach the recipient’s immune system to accept the new organ and reduce the need for long-term immunosuppression.

Initiated by the UPMC Immune Transplant and Therapy Center.

  Trial Eligibility

This study is open to adults between the ages of 18 and 55. For additional requirements and criteria please visit the NIH Clinical Trials website.

Start Date: August 30, 2017
End Date: June 2023

Learn more about this trial on its NIH Clinical Trials webpage or call Mindi Styn, PhD, 412-383-8884.

  Lab Team

Principal Investigators:
Abhinav Humar, MD
Angus Thomson, PhD, DSc

Contact Information

For more information, call the UPMC Immune Transplant and Therapy Center at 1-888-4UPMC-ITTC (1-888-487-6248).

UPMC
200 Lothrop St.
Pittsburgh, PA 15213-2582

Additional Resources

For patients:
UPMC Transplant Services
Immunotherapy at UPMC Hillman Cancer Center
The Aging Institute

For researchers:
Thomas E. Starzl Transplantation Institute
Cancer Immunotherapy Research at UPMC Hillman Cancer Center
University of Pittsburgh Department of Immunology

© 2023 UPMC – The UPMC Immune Transplant and Therapy Center is a partnership between UPMC and the University of Pittsburgh.

  • Contact UPMC
  • UPMC Medical Advice Disclaimer
  • UPMC Privacy Information
  • UPMC Website & Email Terms of Use Policy